Ameloblastic fibro-odontoma (AFO) is a benign, slow growing, expansile epithelial odontogenic tumor with odontogenic mesenchyme. Looking for online definition of ameloblastic odontoma in the Medical Dictionary? ameloblastic odontoma explanation free. What is ameloblastic odontoma?. Riddett S.A.A Composite Odontome at a Very Early Age. Brit. Dent. J., 77 (), p. Google Scholar. 2. Kemper J.W., Root to-odontoma. Amer.

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Histopathological study is mandatory in order to differentiate between these two conditions. Cowden syndrome is an autosomal dominant multiple hamartoma syndrome with PTEN mutations. An analysis of the interrelationship of the mixed odontogenic tumors-ameloblastic fibroma, ameloblastic fibro-odontoma, and the odontomas. Frequently associated with an unerupted tooth Usually detected on routine radiographs Most commonly located between roots of erupted ameloblastjc or impeding the eruption of tooth Well marginated from surrounding bone May have a thin radiolucent region surrounding opaque mass Radiopaque matrix same density as components amelolbastic adjacent teeth Early stage odontoma may have little calcified matrix, expanding the radiographic differential diagnosis Can occur as a component of combined odontogenic tumor, most commonly Calcifying kdontoma odontogenic tumor CCOT Multiple odontomas may occur zmeloblastic a component of: Postoperative recovery was absolutely uneventful.

Many authors reported that AFO can be treated adequately through a surgical curettage without removal of the adjacent teeth [ 14578 ]. AFO susually affects children or young adults, with no specific sex predilection.

It has been reported in the literature under a variety of names including odontoblastoma, 1 adamantoodontoma, 2 calcified mixed odontogenic tumor, 3 and soft and calcified odontoma.

View at Google Scholar N. The mandibular left second molar was not present Figure 1.

International Journal of Dentistry

The table compares Gorlin’s survey composed of his own case plus those cases reported in the earlier literature which he thought belonged in this diagnostic category with Hooker’s survey 26 cases. This is an open access article distributed under the Creative Commons Attribution Licensewhich permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The tumor mass is surrounded by a fibrous capsule and is composed predominantly of a fibroblastic connective tissue matrix containing strands of odontogenic epithelium and immature tooth structures, including enamel and dentin.

This lesion usually occurs in people less than 20 years old, and age is thus an important characteristic in the differential diagnosis. In addition, odontogenic epithelial cells follicles are visualized with a few stellate cells suggestive of AFO.

Sign oodntoma to access your subscriptions Sign in to your personal account. Click here for patient related inquiries. Lesion in left side of the mandible. Abstract An ameloblastic fibroodontoma AFO is a rare odontogenic tumor of mixed dental tissue origin.

It is caused by PTCH1 mutations. Well defined multiple radiopacities. Contributed by Kelly Magliocca, D. This appearance suggests that the lesion is a complex odontoma. Supernumerary teeth Complete well formed teeth Usually in males Can rarely be associated with syndromes such as cleidocranial dysostosis General: Financial support and sponsorship Nil. Gorlin syndrome, also known as nevoid basal cell carcinoma syndrome, is associated with basal cell carcinomas, odontogenic keratocysts ameloblatic fibromas ovarian and heart.

Images hosted on PathOut server: Board review answer 1. De Pedro Marina, and L. Despite numerous efforts, however, there is still considerable confusion concerning the nature of these lesions [ 17 ].

Radiography shows a well-defined, radiolucent area containing various amounts of radiopaque material of irregular size and form [ 45 ].

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This lesion occupied a zone from the lower left second molar area to the left ramus. It may inhibit tooth eruption or displace involved teeth although teeth in the affected area are vital [ 1 — 3 ]. Malformed tooth developing in area of prior trauma Could be histologically identical to complex odontoma Osteoma Benign neoplasm composed of mature lamellar bone compact, trabecular or both Can also affect craniofacial bones Should not have odontogenic epithelium Ameloblastic fibro-odontoma AFO Has biphasic mesenchymal and odontogenic epithelium “soft tissue” component that is identical to ameloblastic fibroma Also contains a calcifying component composed of enamel and dentin structures Most recent WHO Classification of Head and Neck Tumours regards most cases of AFO as developing odontomas rather than a distinct tumor IARC: An year-old girl presented to our department to have a second opinion regarding a lesion involving her left mandible.



Preoperative photograph showing diffuse swelling over the left side of the lower face. Oral surg Oral Med Oral pathol. It occurs with equal frequency in the maxilla and the mandible and with equal frequency in males and females [ 6 ]. An year-old female presented to our unit with the complaint of a painless swelling on the left side of the lower jaw for the last 3 years that seemed to show a progressive increase in size.

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Ameloblastic odontoma | definition of ameloblastic odontoma by Medical dictionary

The tumor was approached via submandibular incision, followed by layer-wise ameloblaztic to reach the inferior border of the mandible. Gardner syndrome familial colorectal polyposis Otodental syndrome Multiple supernumerary teeth similar radiographic appearance can occur as a ameloblasti of cleidocranial dysostosis or arise in non syndromic setting. Ameloblastic fibroodontoma, complex odontoma, mandible, odontogenic tumor.

We report a case of an year-old female patient with missing mandibular molars on the left side associated with a giant complex odontoma. The tumor was excised with 0. Histopathological study revealed it as an AFO, to our surprise. A long-standing case of AFO may progress to complex odontoma.